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Bhavani Lab

 

Critical Precision: Our lab's mission is to transform outcomes for critically ill patients by creating data-driven precision medicine solutions that can be deployed on a global scale.

Recent work

Distinct immune profiles and clinical outcomes in sepsis subphenotypes based on temperature trajectories

Intensive Care Medicine, 2024

Racial Differences in Accuracy of Predictive Models for High-Flow Nasal Cannula Failure in COVID-19
 

CCE, 2024

The Precision Resuscitation With Crystalloids in Sepsis (PRECISE) Trial: A Trial Protocol

Jama Network Open, 2024

Comparison of time series clustering methods for identifying novel subphenotypes of patients with infection

JAMIA, 2023

Using Trajectories of Bedside Vital Signs to Identify COVID-19 Subphenotypes
 

CHEST, 2024

Temperature Trajectory Subphenotypes in Oncology Patients with Neutropenia and Suspected Infection

AJRCCM, 2023

Media highlights

Yahoo News

Tech Target

Kaiser Permanente 

Team

Megan Schwinne, Biomedical Informatics
Chad Robichaux, Biomedical Informatics
Phil Yang, Department of Medicine
Jamie Felzer, Department of Medicine
Danni Miltz, Emory Critical Care Center
Li Xiong, Department of Computer Science
Sam Khan, Department of Anesthesiology
Greg Martin, Department of Medicine
Jon Sevranksy, Department of Medicine
Craig Coopersmith, Director of Emory Critical Care Center
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PRECISE trial

The Precision Resuscitation with Crystalloids in Sepsis (PRECISE) trial is one of the first precision medicine trials of crystalloid fluids in sepsis. Using routine vital signs (temperature, heart rate, respiratory rate, and blood pressure), available even in low-resource settings, a validated machine learning algorithm will prospectively identify and enroll patients with group D sepsis who may have a substantial mortality reduction from used of balanced crystalloids compared with normal saline.

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